Elyas - Oct 13, 2015 04:14 PM EDT mss glittery / AbstractBACKGROUND & AIMS: Because the mode of Crohn's disasee inheritance is unknown, age-adjusted risk estimates and knowledge of disasee characteristics will aid genetic counseling and modeling. The aim of this study is to determine the prevalence of familial occurrence of inflammatory bowel disasee in first-degree relatives of patients with Crohn's disasee and estimate their age-adjusted risks. It also evaluates agreement in disasee characteristics between generations within families with a history of Crohn's disasee. METHODS: Six hundred forty patients with Crohn's disasee and 800 control subjects were questioned about the occurrence of inflammatory bowel disasee in their first-degree relatives. Agreement for age at diagnosis, initial disasee location, disasee behavior, and number of bowel resections was determined in 68 families with two or more members affected and compared with data in 100 unrelated patients with Crohn's disasee. RESULTS: Probands with Crohn's disasee had a more frequent positive family history than controls. The age at diagnosis between probands with and without a positive family history was insignificant. Crude and age-adjusted risk elements were higher in relatives of patients, especially daughters, compared with those of controls. The age at diagnosis was older for parents than offspring but similar between siblings. Initial disasee location was especially striking between siblings. CONCLUSIONS: This study confirms familial aggregation and a high degree of disasee concordance in Crohn's disasee. The age at diagnosis and initial disasee location was especially strong within generations. (Gastroenterology 1996 Sep;111(3):597-603)
Guest - Nov 09, 2004 12:51 AM EDT It is an excellent pictures...
Guest - Sep 14, 2004 08:25 PM EDT i think this is a great pic
Guest - Sep 14, 2004 11:35 AM EDT Very nice portrait. Love the expression you caught!
Guest - Sep 14, 2004 12:27 AM EDT sure is. reminds me a lot of our "grand" Jess.
Guest - Sep 13, 2004 11:16 PM EDT What a beautiful b&w portrait - it really enhances a lovely photo.
Guest - Sep 13, 2004 09:20 PM EDT WOW !!! What a great shot, and expression in her eyes. I like it.
Guest - Sep 13, 2004 06:10 PM EDT She sure is a cutie!!!